Molecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive Molecules

  title={Molecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive Molecules},
  author={Dorothy Moseti and Alemu Regassa and W K Kim and Giovanni Tarantino},
  booktitle={International journal of molecular sciences},
Adipogenesis is the process by which precursor stem cells differentiate into lipid laden adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene expression program. In mammalian cells, the peroxisome proliferator-activated receptor γ (PPARγ), and the CCAAT/enhancer binding proteins (C/EBPs) such as C/EBPα, β and δ are considered the key early regulators of adipogenesis, while fatty acid binding protein 4 (FABP4), adiponectin, and fatty acid synthase (FAS) are responsible… CONTINUE READING


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