Molecular Rac 1 Induces the Clustering of AMPA Receptors during Spinogenesis

@inproceedings{Wiens2005MolecularR1,
  title={Molecular Rac 1 Induces the Clustering of AMPA Receptors during Spinogenesis},
  author={Katie M. Wiens and Hang Lin and Dezhi Liao},
  year={2005}
}
Glutamatergic synapses switch from nonspiny synapses to become dendritic spines during early neuronal development. Here, we report that the lack of sufficient Rac1, a small RhoGTPase, contributes to the absence of spinogenesis in immature neurons. The overexpression of green fluorescence protein-tagged wild-type Rac1 initiated the formation of dendritic… CONTINUE READING