Molecular Profiling Predicts the Existence of Two Functionally Distinct Classes of Ovarian Cancer Stroma

@inproceedings{Lili2013MolecularPP,
  title={Molecular Profiling Predicts the Existence of Two Functionally Distinct Classes of Ovarian Cancer Stroma},
  author={Loukia N Lili and Lilya V. Matyunina and L. DeEtte Walker and Benedict B. Benigno and John F McDonald},
  booktitle={BioMed research international},
  year={2013}
}
Although stromal cell signaling has been shown to play a significant role in the progression of many cancers, relatively little is known about its importance in modulating ovarian cancer development. The purpose of this study was to investigate the process of stroma activation in human ovarian cancer by molecular analysis of matched sets of cancer and surrounding stroma tissues. RNA microarray profiling of 45 tissue samples was carried out using the Affymetrix (U133 Plus 2.0) gene expression… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 45 references

and H

N. A. Bhowmick, E. G. Neilson
L. Moses, “Stromal fibroblasts in cancer initiation and progression,” Nature, vol. 432, no. 7015, pp. 332–337 • 2004
View 4 Excerpts
Highly Influenced

Fibroblast growth factor signalling: from development to cancer

Nature Reviews Cancer • 2010
View 2 Excerpts
Highly Influenced

Tumor stroma and regulation of cancer development.

Annual review of pathology • 2006
View 1 Excerpt
Highly Influenced

L.Moses, “Tumor-stroma interactions,

N. A. Bhowmick andH
Current Opinion in Genetics and Development, • 2005
View 2 Excerpts
Highly Influenced

S

S. Yoshioka, M. L. King
Ran et al., “WNT7A regulates tumor growth and progression in ovarian cancer through theWNT/βcatenin pathway,” Molecular Cancer Research, vol. 10, no. 3, pp. 469–482 • 2012

WNT 7 A regulates tumor growth and progression in ovarian cancer through theWNT / β - catenin pathway

A. B. Tchagang, A. H. Tewfik, M. S. DeRycke, K. M. Skubitz, A. P. N. Skubitz
Molecular Cancer Research • 2012

A

A. Silva
Gı́rio, I. Cebola, C. I. Santos, F. Antunes, and J. T. Barata, “Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells,” Leukemia, vol. 25, no. 6, pp. 960–967 • 2011
View 1 Excerpt

A.Weinberg, “Hallmarks of cancer: the next generation,

R. D. Hanahan
Cell, vol. 144, • 2011
View 1 Excerpt

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