Molecular Mechanisms of Preeclampsia.

  title={Molecular Mechanisms of Preeclampsia.},
  author={Tammy Hod and A. Cerdeira and Siddharth Karumanchi},
  journal={Cold Spring Harbor perspectives in medicine},
  volume={5 10}
Preeclampsia is a pregnancy-specific disease characterized by new onset hypertension and proteinuria after 20 wk of gestation. It is a leading cause of maternal and fetal morbidity and mortality worldwide. Exciting discoveries in the last decade have contributed to a better understanding of the molecular basis of this disease. Epidemiological, experimental, and therapeutic studies from several laboratories have provided compelling evidence that an antiangiogenic state owing to alterations in… CONTINUE READING
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