Molecular Mechanisms of Diabetic Retinopathy: Potential Therapeutic Targets

@inproceedings{Coucha2015MolecularMO,
  title={Molecular Mechanisms of Diabetic Retinopathy: Potential Therapeutic Targets},
  author={Maha Coucha and Sally L. Elshaer and Wael S. Eldahshan and Barbara Ann Mysona and Azza B El-Remessy},
  booktitle={Middle East African journal of ophthalmology},
  year={2015}
}
Diabetic retinopathy (DR) is the leading cause of blindness in working-age adults in United States. Research indicates an association between oxidative stress and the development of diabetes complications. However, clinical trials with general antioxidants have failed to prove effective in diabetic patients. Mounting evidence from experimental studies that continue to elucidate the damaging effects of oxidative stress and inflammation in both vascular and neural retina suggest its critical role… CONTINUE READING
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