Molecular Mechanisms and New Treatment Strategies for Non-Alcoholic Steatohepatitis (NASH)

@inproceedings{Takaki2014MolecularMA,
  title={Molecular Mechanisms and New Treatment Strategies for Non-Alcoholic Steatohepatitis (NASH)},
  author={Akinobu Takaki and Daisuke Kawai and Kazuhide Yamamoto},
  booktitle={International journal of molecular sciences},
  year={2014}
}
Non-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease (NAFLD), in which most patients exhibit non-progressive, non-alcoholic fatty liver (NAFL) attributable to simple steatosis. Multiple hits, including genetic differences, fat accumulation, insulin resistance and intestinal microbiota changes, account for the progression of NASH. NAFLD is strongly associated with obesity, which induces adipokine secretion, endoplasmic reticulum (ER) and oxidative stress at… CONTINUE READING
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