Molecular Mechanism of Androgen Action

@article{Hiipakka1998MolecularMO,
  title={Molecular Mechanism of Androgen Action},
  author={R. Hiipakka and S. Liao},
  journal={Trends in Endocrinology & Metabolism},
  year={1998},
  volume={9},
  pages={317-324}
}
  • R. Hiipakka, S. Liao
  • Published 1998
  • Biology, Medicine
  • Trends in Endocrinology & Metabolism
  • Androgens affect the growth and development of a wide variety of cell types in both males and females and produce their effects by binding to androgen receptors, which modulate the transcription of specific genes. Testosterone is the major active androgen circulating in blood, but in many tissues it is metabolized by 5alpha-reductase to 5alpha-dihydrotestosterone, which binds to and activates the androgen receptor. Androgen receptors are members of the nuclear receptor family of transcription… CONTINUE READING
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