Molecular Koch's postulates applied to microbial pathogenicity.

  title={Molecular Koch's postulates applied to microbial pathogenicity.},
  author={Stanley Falkow},
  journal={Reviews of infectious diseases},
  volume={10 Suppl 2},
  • S. Falkow
  • Published 1 August 1988
  • Biology
  • Reviews of infectious diseases
Microbial genetics and molecular cloning now permit us to routinely isolate specific genes from a variety of microbial pathogens. Obviously not all genes from pathogenic microorganisms play a role in pathogenicity or virulence. Just as Koch's postulates were formulated to identify the causal relationship between an organism and a specific disease, the notion is presented here that a form of molecular Koch's postulates is needed when examining the potential role of genes and their products in… 
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    Journal of the Royal College of Physicians of London
  • 1993
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Causation and Disease: The Henle-Koch Postulates Revisited 1
  • A. Evans
  • Medicine
    The Yale journal of biology and medicine
  • 1976
The Henle-Koch postulates are reviewed in terms of their full validity in Koch's day and in light of subsequent developments, and a set of guidelines for both acute infectious and chronic diseases is presented.