Molecular Insights into mRNA Transport and Local Translation in the Mammalian Nervous System

@article{Kiebler2000MolecularII,
  title={Molecular Insights into mRNA Transport and Local Translation in the Mammalian Nervous System},
  author={Michael A Kiebler and Luc Desgroseillers},
  journal={Neuron},
  year={2000},
  volume={25},
  pages={19-28}
}
reported to be selectively targeted to dendrites of CNS neurons (reviewed by Bashirullah et al. (glycine receptors, glutamate receptors). Do these targeted mRNAs simply reach dendrites by Canada a passive mechanism or is there an active sorting mechanism involved? First, recent work has clearly demonstrated that certain neuronal mRNAs (␣ subunit of CaM-It… CONTINUE READING