Molecular Inclusion Complex of Curcumin–β-Cyclodextrin Nanoparticle to Enhance Curcumin Skin Permeability from Hydrophilic Matrix Gel

@article{Rachmawati2013MolecularIC,
  title={Molecular Inclusion Complex of Curcumin–β-Cyclodextrin Nanoparticle to Enhance Curcumin Skin Permeability from Hydrophilic Matrix Gel},
  author={Heni Rachmawati and Citra Ariani Edityaningrum and Rachmat Mauludin},
  journal={AAPS PharmSciTech},
  year={2013},
  volume={14},
  pages={1303-1312}
}
Curcumin (CUR) has various pharmacological effects, but its extensive first-pass metabolism and short elimination half-life limit its bioavailability. Therefore, transdermal application has become a potential alternative to delivery CUR. To increase CUR solubility for the development of a transparent homogenous gel and also enhance the permeation rate of CUR into the skin, β-cyclodextrin–curcumin nanoparticle complex (BCD–CUR-N) was developed. CUR encapsulation efficiency was increased by… CONTINUE READING
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References

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Cyclodextrin - based nanosponges of curcumin : formulation and physicochemical characterization

  • SS Darandale, PR Vavia
  • J Incl Phenom Macrocycl Chem
  • 2012

Effect of cyclodextrin complexation of curcumin on its solubility and antiangiogenic and anti - inflammatory activity in rat colitis model

  • RY Vivek, S Sarasija, D Kshama, Y Seema
  • AAPS Pharm Sci Tech
  • 2009

Method to enhance the encapsulation of biologically active molecules in PLGA nanoparticles

  • S Sourabhan, K Kaladhar, CP Sharma
  • Trends Biomater Artif Organs
  • 2009

Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature

  • P. Anand
  • Biochem Pharma
  • 2008
1 Excerpt

Vibrational dynamics of inclusion complexes by Raman scattering : an experimental and numerical study

  • B Rossi, P Verrocchio, G Villiani
  • Phil Mag
  • 2007

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