Molecular Hydrogen as an Energy Source for Helicobacter pylori

  title={Molecular Hydrogen as an Energy Source for Helicobacter pylori},
  author={J. Olson and R. Maier},
  pages={1788 - 1790}
  • J. Olson, R. Maier
  • Published 2002
  • Medicine, Biology
  • Science
  • The gastric pathogen Helicobacter pylori is known to be able to use molecular hydrogen as a respiratory substrate when grown in the laboratory. We found that hydrogen is available in the gastric mucosa of mice and that its use greatly increased the stomach colonization by H. pylori. Hydrogenase activity inH. pylori is constitutive but increased fivefold upon incubation with hydrogen. Hydrogen concentrations measured in the stomachs of live mice were found to be 10 to 50 times as high as theH… CONTINUE READING
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