Molecular Evolutionary Analysis of the Influenza A(H1N1)pdm, May–September, 2009: Temporal and Spatial Spreading Profile of the Viruses in Japan

@inproceedings{Shiino2010MolecularEA,
  title={Molecular Evolutionary Analysis of the Influenza A(H1N1)pdm, May–September, 2009: Temporal and Spatial Spreading Profile of the Viruses in Japan},
  author={Teiichiro Shiino and Nobuhiko Okabe and Yoshinori Yasui and T. Sunagawa and Makoto Ujike and Masatsugu Obuchi and Noriko Kishida and Hong Xu and Emi Takashita and Akane Anraku and Reiko Ito and Teruko Doi and Miho Ejima and Hiromi Sugawara and Hiroshi Horikawa and Shuji Yamazaki and Yumiko Kato and Akio Oguchi and Nobuyuki Fujita and Takato Odagiri and Masato Tashiro and Haruo Watanabe},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND In March 2009, pandemic influenza A(H1N1) (A(H1N1)pdm) emerged in Mexico and the United States. In Japan, since the first outbreak of A(H1N1)pdm in Osaka and Hyogo Prefectures occurred in the middle of May 2009, the virus had spread over 16 of 47 prefectures as of June 4, 2009. METHODS/PRINCIPAL FINDINGS We analyzed all-segment concatenated genome sequences of 75 isolates of A(H1N1)pdm viruses in Japan, and compared them with 163 full-genome sequences in the world. Two analyzing… CONTINUE READING