Molecular Evolution of the Periphilin Gene in Relation to Human Endogenous Retrovirus M Element

@article{Huh2005MolecularEO,
  title={Molecular Evolution of the Periphilin Gene in Relation to Human Endogenous Retrovirus M Element},
  author={Jae-Won Huh and Tae-hyung Kim and Jijun Yi and Eun-sil Park and Woo-Yeon Kim and Ho-Su Sin and Dae-Soo Kim and Do-Sik Min and Sang-Soo Kim and Chang-Bae Kim and B Hyun and Soo Kang and Jin-Sup Jung and Won-Ho Lee and Osamu Takenaka and Heui-Soo Kim},
  journal={Journal of Molecular Evolution},
  year={2005},
  volume={62},
  pages={730-737}
}
HERV-M (human endogenous retrovirus M), related to the super family of HERV-K, has a methionine (M) tRNA primer-binding site, and is located within the periphilin gene on human chromosome 12q12. HERV-M has been integrated into the periphilin gene as the truncated form, 5′LTR-gag-pol-3′LTR. Polymerase chain reaction (PCR) and reverse transcription-polymerase chain reaction (RT-PCR) approaches were conducted to investigate its evolutionary origins. Interestingly, the insertion of retroelements in… CONTINUE READING

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Highly Influenced

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