Molecular Epidemiology of O139 Vibrio cholerae: Mutation, Lateral Gene Transfer, and Founder Flush

@inproceedings{Garg2003MolecularEO,
  title={Molecular Epidemiology of O139 Vibrio cholerae: Mutation, Lateral Gene Transfer, and Founder Flush},
  author={Pallavi Garg and Antonia Aydanian and David V. Smith and J. Glenn Morris and Gopinath Balakrish Nair and Oscar Colin Stine},
  booktitle={Emerging infectious diseases},
  year={2003}
}
Vibrio cholerae in O-group 139 was first isolated in 1992 and by 1993 had been found throughout the Indian subcontinent. This epidemic expansion probably resulted from a single source after a lateral gene transfer (LGT) event that changed the serotype of an epidemic V. cholerae O1 El Tor strain to O139. However, some studies found substantial genetic diversity, perhaps caused by multiple origins. To further explore the relatedness of O139 strains, we analyzed nine sequenced loci from 96… CONTINUE READING
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