Molecular Dynamics Study of Protein Deformation through Solid-State Nanopore

  title={Molecular Dynamics Study of Protein Deformation through Solid-State Nanopore},
  author={Mohammad R. Hasan and Mohammed A. I. Mahmood and Raja Raheel Khanzada and Nuzhat Mansur and Ashfaq Adnan and Samir M. Iqbal},
Electrophoretic translocation through solid-state nanopores is a promising technique for identification of specific proteins and protein complexes. In a typical protein detection experiment, an external electric field (e-field) is applied across the nanopore and the ionic current is measured while the molecule passes through the pore. It is very important that the protein retains its structure and functionality under applied e-field and experimental conditions. However, the elongation and… Expand
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