Molecular Docking Simulation of Short-Chain Four Disulphide Bridged Scorpion Toxins with Structural Model of Human Voltage-Gated Potassium

@inproceedings{Kv2009MolecularDS,
  title={Molecular Docking Simulation of Short-Chain Four Disulphide Bridged Scorpion Toxins with Structural Model of Human Voltage-Gated Potassium},
  author={Ion Channel Kv},
  year={2009}
}
  • Ion Channel Kv
  • Published 2009
We report structural model of the human voltage-gated potassium ion channel Kv1.3 obtained based on the crystallographic structure of KcsA by homology modeling. Molecular docking simulations were performed between the model structure of Kv1.3 channel with three short-chain four disulphide bridged scorpion toxins HsTX1 from the venom of Heterometrus spinnifer (Scorpionidae), maurotoxin (MTX) from Scorpiomaurus palmatus and Pandinus toxin 1(Pi1) from Pandinus imperator which belongs to the -KTx6… CONTINUE READING