Molecular Determinants of Binding to the Plasmodium Subtilisin-like Protease 1

@inproceedings{Fulle2013MolecularDO,
  title={Molecular Determinants of Binding to the Plasmodium Subtilisin-like Protease 1},
  author={Simone Fulle and Chrislaine Withers-Martinez and Michael J. Blackman and Garrett M. Morris and Paul W. Finn},
  booktitle={Journal of Chemical Information and Modeling},
  year={2013}
}
PfSUB1, a subtilisin-like protease of the human malaria parasite Plasmodium falciparum, is known to play important roles during the life cycle of the parasite and has emerged as a promising antimalarial drug target. In order to provide a detailed understanding of the origin of binding determinants of PfSUB1 substrates, we performed molecular dynamics… CONTINUE READING