Molecular Configuration in Sodium Thymonucleate

  title={Molecular Configuration in Sodium Thymonucleate},
  author={Rosalind E. Franklin and Raymond G. Gosling},
Perspectives on theory at the interface of physics and biology
  • W. Bialek
  • Physics
    Reports on progress in physics. Physical Society
  • 2018
I am an optimist, and believe that the time is ripe for the emergence of a more unified theoretical physics of biological systems, building on successes in thinking about particular phenomena.
Making Sense of Genes
Making Sense of Genes is an accessible but rigorous introduction to contemporary genetics concepts for non-experts, undergraduate students, teachers and healthcare professionals.
Theoretical Analysis of Competing Conformational Transitions in Superhelical DNA
A statistical mechanical model is developed to analyze the competitive behavior of transitions to multiple alternate conformations in a negatively supercoiled DNA molecule of kilobase length and specified base sequence and shows this competition to be highly sensitive to temperature and to the imposed level of supercoiling.
Beyond the double helix: DNA structural diversity and the PDB
  • S. Neidle
  • Chemistry, Biology
    The Journal of biological chemistry
  • 2021
Alternative DNA Structures In Vivo: Molecular Evidence and Remaining Questions
Evidence supporting the formation of alternative DNA structures in vivo is discussed and the role of the mismatch repair machinery in binding mispaired DNA duplexes, triggering genetic instability is emphasized.
Through the Looking Glass: The AADR and the Wow of Science
In Through the Looking Glass, Lewis Carroll uses a 2-way mirror as a metaphor for seeing ourselves existing in reality while also transporting into our imaginations (Fig. 1). In our imaginations,
Studies towards the prebiotic synthesis and phosphorylation of ribonucleotides
The discovery of a generational node in the network of prebiotic chemistry that links the syntheses of amino acids with nucleotides 5'-phosphates suggests that these different groups of metabolites need not have arisen from separate chemistries, helping to get a better understanding of the processes governing the chemical evolution of life.
Cellular Detection of G‐Quadruplexes by Optical Imaging Methods
A repertoire of protocols that have developed over the past years to visualize quadruplexes in cells are listed, thanks to the discovery of a novel family of versatile quadruplex‐selective fluorophores, the twice‐as‐smart quadruplex ligands named TASQ (for template‐assembled synthetic G‐quartet).
A critical analysis of The Nature of Things
A critical analysis of the ‘science play’ The Nature of Things examining the dramaturgical challenges of integrating biography, science and art. The overall aim was to create an original, imaginative


A Proposed Structure For The Nucleic Acids.
  • L. Pauling, R. Corey
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1953
The proposed structure for the Nucleic Acids is based on X-ray diffraction analysis of Na6(CO3, Na3SO4, Na2SO3, and Na2CO4 using a Higgs boson-like structure.
The structures of nucleic acids.
  • J. M. Gulland
  • Biology, Chemistry
    Symposia of the Society for Experimental Biology
  • 1947
The structure of proteins; two hydrogen-bonded helical configurations of the polypeptide chain.
This work has used information about interatomic distances, bond angles, and other configurational parameters to construct two reasonable hydrogen-bonded helical configurations for the polypeptide chain; it is likely that these configurations constitute an important part of the structure of both fibrous and globular proteins, as well as of syntheticpolypeptides.