Molecular Cloning and Expression of the Leishmania infantum KMP-11 Gene

@inproceedings{Soflaei2013MolecularCA,
  title={Molecular Cloning and Expression of the Leishmania infantum KMP-11 Gene},
  author={Saied Soflaei and Abdolhossein Dalimi and Fatemeh Ghafarifar},
  year={2013}
}
Background: Visceral leishmaniasis (Kala-azar) is one of the most serious tropical diseases, and it can lead to death. The kinetoplastid membrane protein-11 (KMP-11) is highly conserved in all stages of the Leishmania life cycle. Objectives: In the present study, the KMP-11 gene was extracted from Leishmania infantum and then, cloned and expressed in an expression vector.The main objective of this study was to provide an introduction to DNA vaccine production against visceral leishmaniasis… CONTINUE READING