Molecular Cloning, Functional Expression and Pharmacological Characterization of the Human Metabotropic Glutamate Receptor Type 2

@article{Flor1995MolecularCF,
  title={Molecular Cloning, Functional Expression and Pharmacological Characterization of the Human Metabotropic Glutamate Receptor Type 2},
  author={P. Flor and K. Lindauer and I. P{\"u}ttner and D. Rüegg and S. Lukic and T. Kn{\"o}pfel and R. Kuhn},
  journal={European Journal of Neuroscience},
  year={1995},
  volume={7}
}
A cDNA encoding the human metabotropic glutamate receptor type 2 (hmGluR2) was isolated from human brain cDNA libraries by cross‐hybridization with rat mGluR2 probes. The deduced amino acid sequence of the human mGluR2 receptor consists of 872 residues and shows a sequence identity of 97% to the amino acid sequence of rat mGluR2. Northern blot analyses showed that hmGluR2 is widely expressed in different regions of the adult brain as well as in fetal human brain. Genomic Southern blotting… Expand
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Cloning and characterization of alternative mRNA forms for the rat metabotropic glutamate receptors mGluR7 and mGluR8
  • C. Corti, Sophie Restituito, +4 authors Francesco Ferraguti
  • Biology, Medicine
  • The European journal of neuroscience
  • 1998
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