Molecular Characterization of Non-Human Primate Zona Pellucida Glycoproteins

  title={Molecular Characterization of Non-Human Primate Zona Pellucida Glycoproteins},
  author={S. Gupta and C. Govind and D. Senthil and M. Srivastava and P. Jethanandani and R. Kaul and A. Mittal and Neela Sivapurapu and P. Sheela},
  • S. Gupta, C. Govind, +6 authors P. Sheela
  • Published 1999
  • Chemistry
  • Zona pellucida is comprised of three distinct families of glycoproteins, ZP1, ZP2 and ZP3 which plays an important role at various stages of fertilization. To elucidate further the potential of ZP glycoproteins as candidate antigens for design of an immunocontraceptive vaccine, we have characterized the bonnet monkey (Macaca radiata) bmZPl, bmZP2 and bmZP3. bmZPl, bmZP2 and bmZP3 reveal 92.0%, 92.2% and 93.9% amino acid sequence identity with human (h) hZP1, hZP2 and hZP3 respectively. The… CONTINUE READING
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