Molecular Characterization of Circulating Tumor Cells in Human Metastatic Colorectal Cancer

@inproceedings{Barbazn2012MolecularCO,
  title={Molecular Characterization of Circulating Tumor Cells in Human Metastatic Colorectal Cancer},
  author={Jorge Barbaz{\'a}n and Lorena Alonso-Alconada and Laura Muinelo-Romay and Mar{\'i}a Vieito and Alicia Abalo and Marta Alonso-Nocelo and Sonia Candamio and Elena Gallardo and Beatriz Fern{\'a}ndez and Ihab Abdulkader and Mar{\'i}a de los {\'A}ngeles Casares and Antonio G{\'o}mez-Tato and Rafael L{\'o}pez-L{\'o}pez and Miguel Abal},
  booktitle={PloS one},
  year={2012}
}
Metastatic colorectal cancer (mCRC) relies on the detachment of aggressive malignant cells from the primary tumor into the bloodstream and, concordantly, the presence of these Circulating Tumor Cells (CTC) is associated with a poor prognosis. In this work, the molecular characterization of CTC from mCRC patients was approached, with the aim of understanding their biology and improving their clinical utility in the management of colorectal cancer patients. For this, EpCAM-based immunoisolation… CONTINUE READING