Molecular Basis of Triple Negative Breast Cancer and Implications for Therapy

  title={Molecular Basis of Triple Negative Breast Cancer and Implications for Therapy},
  author={Parvin F. Peddi and Matthew J. Ellis and Cynthia X. Ma},
  booktitle={International journal of breast cancer},
Triple negative breast cancer is an aggressive form of breast cancer with limited treatment options and is without proven targeted therapy. Understanding the molecular basis of triple negative breast cancer is crucial for effective new drug development. Recent genomewide gene expression and DNA sequencing studies indicate that this cancer type is composed of a molecularly heterogeneous group of diseases that carry multiple somatic mutations and genomic structural changes. These findings have… CONTINUE READING


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