Molecular Basis of Congenital Adrenal Hyperplasia Due to 3β-hydroxysteroid Dehydrogenase Deficiency

Abstract

Classical 3β-hydroxysteroid dehydrogenase/Δ5-Δ/) isomerase (3β-HSD) deficiency is an autosomal recessive form of congenital adrenal hyperplasia (CAH). In contrast to CAH due to 21-hydroxylase and 11β-hydroxylase deficiencies, which impair steroid formation in the adrenal cortex exclusively, classical 3β-HSD deficiency affects steroid biosynthesis in the… (More)
DOI: 10.1203/00006450-199305001-00023

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Cite this paper

@article{Simard1993MolecularBO, title={Molecular Basis of Congenital Adrenal Hyperplasia Due to 3β-hydroxysteroid Dehydrogenase Deficiency}, author={Jacques Simard and Yves G. Morel and {\'E}ric Rh{\'e}aume and Roc{\'i}o del Pilar Moreno S{\'a}nchez and Farida Mebarki and Nathalie Laflamme and Maria I. New and Fernand Labrie}, journal={Pediatric Research}, year={1993}, volume={33}, pages={S6-S6} }