Molecular Basis for the Regenerative Properties of a Secretion of the Mollusk Cryptomphalus aspersa

  title={Molecular Basis for the Regenerative Properties of a Secretion of the Mollusk Cryptomphalus aspersa},
  author={Aurora Brieva and Neena Philips and Reyes Tejedor and Antonio Guerrero and Juan Pablo Pivel and José Luis Alonso-Lebrero and Salvador Gonz{\'a}lez},
  journal={Skin Pharmacology and Physiology},
  pages={15 - 22}
A screen for natural products bearing pharmacological properties has yielded a secretion of the mollusk Cryptomphalus aspersa (SCA), which possesses skin-regenerative properties. In this report, we outline some of the cellular and molecular effects underlying this observation. First, we found that SCA contained antioxidant SOD and GST activities. In addition, SCA stimulated fibroblast proliferation and rearrangement of the actin cytoskeleton. Additional mechanisms involved in the regenerative… 

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