Molecular Basis for Cross-Linking of Actin Filaments: Structure of the α-Actinin Rod

Abstract

Structural Biology Programme peats, and a calmodulin-like domain at the carboxy ter-It is a dimer composed of D-69012 Heidelberg two 100 kDa monomers that are arranged in an antiparal-Germany lel manner to form a rod-shaped molecule with an actin-binding region at either end (Figure 1C). This arrangement allows ␣-actinin to cross-link actin filaments into… (More)
DOI: 10.1016/S0092-8674(00)81981-9

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