Molecular BKology: the study of splicing and dicing.

  title={Molecular BKology: the study of splicing and dicing.},
  author={Matthew G. Fury and Steven O. Marx and Andrew Robert Marks},
  journal={Science's STKE : signal transduction knowledge environment},
  volume={2002 123},
The activity of ion channels is regulated by several different mechanisms. Studies have been undertaken to determine how the large-conductance Ca(2+)-sensitive K(+) channel (the BK channel) is regulated. Fury et al. discuss how the presence or absence of alternatively spliced regions in the BK channel alpha subunit can act as a molecular switch by which different kinases activate the BK channel. 

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