Molecular Analysis of Healing at a Bone-Implant Interface

@article{Colnot2007MolecularAO,
  title={Molecular Analysis of Healing at a Bone-Implant Interface},
  author={C{\'e}line Colnot and D. H. Malag{\'o}n Romero and S. Huang and J Rahman and Jennifer A. Currey and Antonio Nanci and John B. Brunski and Jill A. Helms},
  journal={Journal of Dental Research},
  year={2007},
  volume={86},
  pages={862 - 867}
}
While bone healing occurs around implants, the extent to which this differs from healing at sites without implants remains unknown. We tested the hypothesis that an implant surface may affect the early stages of healing. In a new mouse model, we made cellular and molecular evaluations of healing at bone-implant interfaces vs. empty cortical defects. We assessed healing around Ti-6Al-4V, poly(L-lactide-co-D,L,-lactide), and 303 stainless steel implants with surface characteristics comparable… 

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