Molecular Alteration Analysis of Human Gut Microbial Composition in Graves' disease Patients

  title={Molecular Alteration Analysis of Human Gut Microbial Composition in Graves' disease Patients},
  author={Hafiz Muhammad Ishaq and I. Mohammad and M. Shahzad and C. Ma and M. Raza and X. Wu and Hui Guo and Peijie Shi and J. Xu},
  journal={International Journal of Biological Sciences},
  pages={1558 - 1570}
  • Hafiz Muhammad Ishaq, I. Mohammad, +6 authors J. Xu
  • Published 2018
  • Biology, Medicine
  • International Journal of Biological Sciences
  • The gut microbial association with host co-existence is critical for body homeostasis and pathogenicity. Graves' disease (GD) is an autoimmune disease manifested with hyperthyroidism and ophthalmopathy. However, we hypothesized that gut bacteria could affect an important role in GD pathogenicity. The current study aim was to characterize and investigate the intestinal bacterial composition of GD qualitatively and quantitatively. 27 GD and 11 healthy controls were enrolled for fecal sample… CONTINUE READING
    23 Citations

    Paper Mentions

    Observational Clinical Trial
    It has been shown that gut microbiome and microbiome metabolism can regulate or control the initiation of a cancer process. To the best of the investigators knowledge, no study has… Expand
    ConditionsMicrobiome, Papillary Thyroid Microcarcinoma
    Intestinal microbiota changes in Graves’ disease: a prospective clinical study
    • 1
    • PDF
    Gut dysbiosis contributes to the imbalance of Treg and Th17 cells in Graves' disease patients by propionic acid.
    • 1
    Comparative assessment of gut microbial composition and function in patients with Graves’ disease and Graves’ orbitopathy
    • 2
    Associations between gut microbiota and thyroidal function status in Chinese patients with Graves’ disease
    Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patients
    • 5
    • Highly Influenced


    Molecular estimation of alteration in intestinal microbial composition in Hashimoto's thyroiditis patients.
    • 19
    • PDF
    Gut Microbe Analysis Between Hyperthyroid and Healthy Individuals
    • 36
    • Highly Influential
    The microbiota and autoimmunity: Their role in thyroid autoimmune diseases.
    • 37
    • PDF
    Molecular Characterisation of the Faecal Microbiota in Patients with Type II Diabetes
    • 317
    Molecular Characterization of Skin Microbiota Between Cancer Cachexia Patients and Healthy Volunteers
    • Wei Li, L. Han, +4 authors J. Xu
    • Biology, Medicine
    • Microbial Ecology
    • 2013
    • 17
    Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls
    • 367
    • PDF
    Molecular analysis of the diversity of vaginal microbiota associated with bacterial vaginosis
    • 260
    • PDF
    Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis
    • 1,001
    • PDF