Molecular “Vitalism”

@article{Kirschner2000Molecular,
  title={Molecular “Vitalism”},
  author={M. Kirschner and J. Gerhart and T. Mitchison},
  journal={Cell},
  year={2000},
  volume={100},
  pages={79-88}
}
ate on very different principles. Even the simple signal-response of an allosteric enzyme is not machine-like Berkeley, California 94720 when examined in detail. Allosteric proteins have intrin-sically active and inactive conformations, which exist in some ratio in the absence of an external signal (Monod In the early nineteenth century, views on the nature of et al., 1965; Henry et al., 1997). Interconversion between living organisms were broadly divided into two catego-the states is… Expand
101 Citations
The Noisy and Marvelous Molecular World of Biology
  • PDF
Is the cell really a machine?
  • D. Nicholson
  • Computer Science, Medicine
  • Journal of theoretical biology
  • 2019
  • 48
Cellular self-organization: generating order from the abyss
  • 5
  • PDF
Complexity: the organizing principle at the interface of biological (dis)order
  • 8
On the origin, evolution, and nature of programmed cell death: a timeline of four billion years
  • J. Ameisen
  • Biology, Medicine
  • Cell Death and Differentiation
  • 2002
  • 510
  • PDF
The protein folds as platonic forms: new support for the pre-Darwinian conception of evolution by natural law.
  • 51
  • PDF
Homeostasis as the Mechanism of Evolution
  • 36
  • PDF
Designing Synthetic Regulatory Networks Capable of Self-Organizing Cell Polarization
  • 137
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 43 REFERENCES
Can a two-state MWC allosteric model explain hemoglobin kinetics?
  • 85
Cell Motility by Labile Association of Molecules
  • 713
  • PDF
A physicist looks at bacterial chemotaxis.
  • H. Berg
  • Biology, Medicine
  • Cold Spring Harbor symposia on quantitative biology
  • 1988
  • 56
Cell biology of Tetrahymena thermophila.
  • J. Frankel
  • Biology, Medicine
  • Methods in cell biology
  • 2000
  • 138
CYTOPLASMIC INHERITANCE OF THE ORGANIZATION OF THE CELL CORTEX IN PARAMECIUM AURELIA.
  • J. Beisson, T. M. Sonneborn
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1965
  • 344
  • PDF
Macromolecular matchmaking: advances in two-hybrid and related technologies.
  • 39
Specifying the dorsoanterior axis in frogs: 70 years since Spemann and Mangold.
  • 30
Vance Tartar: A Unique Biologist
  • 7
...
1
2
3
4
5
...