Molecular, functional, and pharmacological targets for the development of gut promotility drugs.

  • Sushil K Sarna
  • Published 2006 in
    American journal of physiology. Gastrointestinal…


The science of gastrointestinal motility has made phenomenal advances during the last fifty years. Yet, there is a paucity of effective promotility drugs to treat functional bowel disorders that affect 10-29% of the U.S. population. A part of the reason for the lack of effective drugs is our limited understanding of the etiology of these diseases. In the… (More)


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