Molecular, Biochemical and Genetic Characteristics of BSE in Canada

  title={Molecular, Biochemical and Genetic Characteristics of BSE in Canada},
  author={S. Dudas and Jianmin Yang and C. Graham and M. Czub and T. McAllister and M. Coulthart and S. Czub},
  journal={PLoS ONE},
  • S. Dudas, Jianmin Yang, +4 authors S. Czub
  • Published 2010
  • Biology, Medicine
  • PLoS ONE
  • The epidemiology and possibly the etiology of bovine spongiform encephalopathy (BSE) have recently been recognized to be heterogeneous. In particular, three types [classical (C) and two atypical (H, L)] have been identified, largely on the basis of characteristics of the proteinase K (PK)-resistant core of the misfolded prion protein associated with the disease (PrPres). The present study was conducted to characterize the 17 Canadian BSE cases which occurred prior to November 2009 based on the… CONTINUE READING
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