Molar substitution and C2/C6 ratio of hydroxyethyl starch: influence on blood coagulation.

@article{Roten2006MolarSA,
  title={Molar substitution and C2/C6 ratio of hydroxyethyl starch: influence on blood coagulation.},
  author={In{\`e}s von Roten and Caveh Madjdpour and Philippe Frascarolo and M Burmeister and Andreas Fisch and S{\"o}ren Schramm and Thomas Bombeli and Donat R Spahn},
  journal={British journal of anaesthesia},
  year={2006},
  volume={96 4},
  pages={455-63}
}
BACKGROUND Development of hydroxyethyl starches (HES) with a low impact on blood coagulation but a long intravascular persistence is of clinical interest. A previous in vitro study showed that low substituted high molecular weight HES does not compromise blood coagulation more than medium molecular weight HES. In the present study we assessed the individual effects on blood coagulation of molar substitution and C2/C6 ratio of a high molecular weight HES. METHODS Blood was obtained from 30… CONTINUE READING

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