Modules in the photoreceptor RGS9-1.Gbeta 5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stability.

@article{He2000ModulesIT,
  title={Modules in the photoreceptor RGS9-1.Gbeta 5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stability.},
  author={Wei He and Lao-fu Lu and Xue Zhang and Heithem M. El-Hodiri and Cammy K-M Chen and Kevin C Slep and Melvin I. Simon and Milan Jamrich and Theodore G Wensel},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 47},
  pages={37093-100}
}
RGS (regulators of G protein signaling) proteins regulate G protein signaling by accelerating GTP hydrolysis, but little is known about regulation of GTPase-accelerating protein (GAP) activities or roles of domains and subunits outside the catalytic cores. RGS9-1 is the GAP required for rapid recovery of light responses in vertebrate photoreceptors and the only mammalian RGS protein with a defined physiological function. It belongs to an RGS subfamily whose members have multiple domains… CONTINUE READING

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Protein Modules in Photoreceptor GAP Complex

  • P. D. Nieuwkoop, J. Faber
  • Methods Cell Biol
  • 1994

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