Modulatory effects on immunoglobulin synthesis and secretion by lymphocytes from immunodeficient patients.

Abstract

Incubation of peripheral lymphocytes (PBL) from normal donors with pokeweek mitogen (PWM) induced terminal differentiation by B lymphocytes to immunoglobulin (Ig) synthesizing and secreting plasma cells. B cells from hypogammaglobulinemic patients with different primary immunodeficiencies failed to undergo functional differentiation after similar treatment… (More)

Topics

Cite this paper

@article{Schwartz1977ModulatoryEO, title={Modulatory effects on immunoglobulin synthesis and secretion by lymphocytes from immunodeficient patients.}, author={Sandy Schwartz and Y. S. Choi and Louie Shou and Robert Alan Good}, journal={The Journal of clinical investigation}, year={1977}, volume={59 6}, pages={1176-87} }