Modulatory effects of new curcumin analogues on gamma-irradiation - Induced nephrotoxicity in rats.

@article{Ismail2016ModulatoryEO,
  title={Modulatory effects of new curcumin analogues on gamma-irradiation - Induced nephrotoxicity in rats.},
  author={Amel F M Ismail and Nashwa H Zaher and Ebaa M. El-Hossary and Marwa G. El-Gazzar},
  journal={Chemico-biological interactions},
  year={2016},
  volume={260},
  pages={141-153}
}
In the present study, a new series of 2-amino-pyran-3-carbonitrile derivatives of curcumin 2-7 have been synthesized via one-pot simple and efficient protocol, involving the reaction of curcumin 1 with substituted-benzylidene-malononitrile to modify the 1,3-diketone moiety. The structures of the synthesized compounds 2-7 were elucidated by microanalytical… CONTINUE READING