Modulatory effect of cAMP on fungal ergosterol level and inhibitory activity of azole drugs.

@article{Sardari2003ModulatoryEO,
  title={Modulatory effect of cAMP on fungal ergosterol level and inhibitory activity of azole drugs.},
  author={Soroush Sardari and Yuichiro Mori and Takao Kurosawa and Mohsen Daneshtalab},
  journal={Canadian journal of microbiology},
  year={2003},
  volume={49 5},
  pages={344-9}
}
The functions and biosynthesis of sterols have been effective targets for fungal control in different areas, including pharmaceutical and agricultural applications. Fungi are among the organisms that synthesize sterols, principally ergosterol. In this paper, the effect of dibutyryl-cAMP (db-cAMP) on ergosterol level and the interaction of drugs that would change the concentration of cAMP with antifungal drugs have been investigated. Sterols were extracted from Candida albicans, and ergosterol… CONTINUE READING