Modulatory action of essential fatty acids on experimental allergic encephalomyelitis (EAE)

@article{Harbige1994ModulatoryAO,
  title={Modulatory action of essential fatty acids on experimental allergic encephalomyelitis (EAE)},
  author={Laurence S. Harbige and Milton M Morris and Sandra Amor},
  journal={Journal of Neuroimmunology},
  year={1994},
  volume={52}
}
Experimental allergic encephalomyelitis (EAE), an autoimmune disease of the CNS mediated by MHC class II restricted CD4 + T lymphocytes, may be induced in mice with spinal cord homogenate (SCH) or the major myelin constituents. Biozzi A B / H (H-2 dql) mice express H-2A n°d, which is homologous to the HLA.DQBI*0302 allele associated with susceptibility to insulin-dependent diabetes and multiple sclerosis in a subset of patients. A B / H mice exhibit a reproducible form of relapsing EAE after… CONTINUE READING

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