Modulatory Effects of l‐Carnitine on Glucocorticoid Receptor Activity

@article{Manoli2004ModulatoryEO,
  title={Modulatory Effects of l‐Carnitine on Glucocorticoid Receptor Activity},
  author={Irini Manoli and MASSIMO U. Martino and Tomoshige Kino and Salvatore Alesci},
  journal={Annals of the New York Academy of Sciences},
  year={2004},
  volume={1033}
}
Abstract: l‐Carnitine (3‐hydroxy‐4‐N,N,N‐trimethylaminobutyrate) is a conditionally essential nutrient with a major role in cellular energy metabolism. It is available in the United States as both a prescription drug and an over‐the‐counter nutritional supplement. Accumulating evidence from both animal and human studies indicates that pharmacologic doses of l‐carnitine (LCAR) have immunomodulatory effects resembling those of glucocorticoids (GC). On the other hand, in contrast to GC, which… 

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