Modulators of Cytoskeletal Reorganization in CA1 Hippocampal Neurons Show Increased Expression in Patients at Mid-Stage Alzheimer's Disease

@inproceedings{Kao2010ModulatorsOC,
  title={Modulators of Cytoskeletal Reorganization in CA1 Hippocampal Neurons Show Increased Expression in Patients at Mid-Stage Alzheimer's Disease},
  author={Patricia F. Kao and David A. Davis and Meredith G. Banigan and Charles R. Vanderburg and Sudha Seshadri and Ivana Delalle},
  booktitle={PloS one},
  year={2010}
}
During the progression of Alzheimer's disease (AD), hippocampal neurons undergo cytoskeletal reorganization, resulting in degenerative as well as regenerative changes. As neurofibrillary tangles form and dystrophic neurites appear, sprouting neuronal processes with growth cones emerge. Actin and tubulin are indispensable for normal neurite development and… CONTINUE READING