Modulators and milieu in preretinal neovascularisation

It has long been established that preretinal neovascular­ isation follows retinal capillary non-perfusion and inner retinal ischaemia,I,2 but the precise mechanism whereby ischaemia stimulates new vessel growth is unclear. Some consider that hypoxia is the sole aetiological factor in pre­ retinal neovascularisation (independent of growth modu­ lators).3,4… CONTINUE READING