Modulative effects of cell adhesion peptide (Arg-Gly-Asp-Ser) on the aggregation of stimulated platelets from ophthalmic patients.


Adhesion proteins are cofactors in the aggregation of human platelets, and can mediate the ADP-induced response of these cells. It was shown that the synthetic cell adhesion peptide, Arg-Gly-Asp-Ser inhibits the aggregation of platelets from normal donors and ophthalmic patients with diabetic retinopathy, glaucoma and retinal vein occlusion. This effect… (More)