Modulations of 17-beta estradiol on osteogenic and adipogenic differentiations of human mesenchymal stem cells.

@article{Hong2006ModulationsO1,
  title={Modulations of 17-beta estradiol on osteogenic and adipogenic differentiations of human mesenchymal stem cells.},
  author={Liu Hong and Aylin Çolpan and Ioana A Peptan},
  journal={Tissue engineering},
  year={2006},
  volume={12 10},
  pages={2747-53}
}
Bone marrow mesenchymal stem cells (MSCs) are a promising cell source for tissue engineering and regenerative medicine applications. However, effective regulation to improve differentiation potentials of MSCs plays a critical role in promoting successful tissue formation. Because estrogen has been demonstrated to modulate tissue and organ development and differentiation, we hypothesized that adding estrogen could effectively improve the multiple differentiation potentials of human bone marrow… CONTINUE READING