• DOI:10.1038/320172A0
Corpus ID: 29697125

Modulation of visual cortical plasticity by acetylcholine and noradrenaline

@article{Bear1986ModulationOV,
  title={Modulation of visual cortical plasticity by acetylcholine and noradrenaline},
  author={M. Bear and W. Singer},
  journal={Nature},
  year={1986},
  volume={320},
  pages={172-176}
}

M. Bear, W. Singer

Published 1986

Biology, Medicine

Nature

During a critical period of postnatal development, the temporary closure of one eye in kittens will permanently shift the ocular dominance (OD) of neurones in the striate cortex to the eye that remains open1. The OD plasticity can be substantially reduced if the cortex is infused continuously with the catecholamine neurotoxin 6-hydroxydopamine (6-OHDA) during the period of monocular deprivation2–5, an effect that has been attributed to selective depletion of cortical noradrenaline6. However… CONTINUE READING

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