Modulation of the transcription regulatory program in yeast cells committed to sporulation

@article{Friedlander2005ModulationOT,
  title={Modulation of the transcription regulatory program in yeast cells committed to sporulation},
  author={Gilgi Friedlander and Daphna Joseph-Strauss and Miri Carmi and Drora Zenvirth and Giora Simchen and Naama Barkai},
  journal={Genome Biology},
  year={2005},
  volume={7},
  pages={R20 - R20}
}
Meiosis in budding yeast is coupled to the process of sporulation, where the four haploid nuclei are packaged into a gamete. This differentiation process is characterized by a point of transition, termed commitment, when it becomes independent of the environment. Not much is known about the mechanisms underlying commitment, but it is often assumed that positive feedback loops stabilize the underlying gene-expression cascade. We describe the gene-expression program of committed cells… CONTINUE READING

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Genome Biology 2006, 7:R20 R20.14

  • AP Gasch, PT Spellman, CM Kao, O Carmel-Harel, MB Eisen, Storz
  • Genome Biology
  • 2006
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