Modulation of the neuronal nicotinic acetylcholine receptor-channel by the nootropic drug nefiracetam.

Abstract

The effects of nefiracetam (DM-9384) on the neuronal nicotinic acetylcholine (ACh) receptor-channel were studied by the whole-cell patch clamp technique using PC12 cells. Nefiracetam had a dual effect on ACh-induced currents: it augmented the currents induced by low concentrations (10-30 microM) of ACh and suppressed those induced by high concentrations… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.