Modulation of the intestinal response to ionizing radiation by anticoagulant and non-anticoagulant heparins.

Abstract

Endothelial dysfunction is involved in radiation responses in many normal tissues, including intestine. Endothelium-directed interventions ameliorate intestinal radiation injury (radiation enteropathy) in animal models, and anecdotal reports also suggest a beneficial effect of heparin. This study assessed low molecular weight heparin as an intestinal… (More)

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