Modulation of the inflammatory response in rats chronically treated with the antidepressant agomelatine.

@article{Molteni2013ModulationOT,
  title={Modulation of the inflammatory response in rats chronically treated with the antidepressant agomelatine.},
  author={Raffaella Molteni and Flavia Macchi and Claudia Zecchillo and Mario Dell'Agli and Elisa Zugno-Barbara Colombo and Francesca Calabrese and Gianluigi Guidotti and Giorgio Racagni and Marco Andrea Riva},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year={2013},
  volume={23 11},
  pages={1645-55}
}
Growing evidence suggests that the activation of the inflammatory/immune system contributes to depression pathogenesis, a hypothesis that might hold strong clinical implication. Indeed more than 30% of depressed patients fail to achieve remission, which poses the necessity to identify systems that may represent novel targets for medications. Accordingly, goal of this study was to evaluate the ability of the antidepressant agomelatine to modulate specific components of the immune response in the… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Genome-wide analysis of LPS-induced inflammatory response in the rat ventral hippocampus: Modulatory activity of the antidepressant agomelatine.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry • 2018
View 12 Excerpts

Similar Papers

Loading similar papers…