Modulation of the human hair follicle pigmentary unit by corticotropin-releasing hormone and urocortin peptides.

Abstract

Human skin is a local source of corticotropin-releasing hormone (CRH) and expresses CRH and CRH receptors (CRH-R) at mRNA and protein levels. Epidermal melanocytes respond to CRH by induction of cAMP with up-regulation of pro-opiomelanocortin gene expression and subsequent production of adrenocorticotropin hormone. However, the role of CRH/CRH-R in… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.