Modulation of the human cytokine response by interferon lambda-1 (IFN-lambda1/IL-29).

@article{Jordan2007ModulationOT,
  title={Modulation of the human cytokine response by interferon lambda-1 (IFN-lambda1/IL-29).},
  author={William James Jordan and Joyce Eskdale and Michele Boniotto and Maria Teresa Rodia and Douglas Kellner and Grant E. Gallagher},
  journal={Genes and immunity},
  year={2007},
  volume={8 1},
  pages={13-20}
}
The interferon lambda family (IFN-lambda1/2/3) is a newly described group of cytokines that are related to both the type-1 interferons and IL-10 family members. These novel cytokines are induced during viral infection and, like type-1 interferons, display significant anti-viral activity. In order to understand their function in more depth, we have examined the ability of IFN-lambda1/IL-29 to regulate cytokine production by human immune cells. Whole peripheral blood mononuclear cells (PBMC… CONTINUE READING
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